Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498587 | 0.88 | CBS (0.41) | EPHX1EPHX2GAAMEN1NPC1 | |
| SCHEMBL9499230 | 0.78 | TSHR (0.39) | GAAMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL9498421 | 0.77 | — | — | |
| SCHEMBL9496918 | 0.76 | KMT2A (0.42) | MEN1NPC1KMT2AALDH1A1RAB9A | |
| SCHEMBL5252939 | 0.76 | RAB9A (0.45) | MEN1NPC1KMT2AALDH1A1RAB9A | |
| SCHEMBL5253142 | 0.75 | MEN1 (0.43) | MEN1NPC1KMT2AALDH1A1RAB9A | |
| SCHEMBL9494535 | 0.74 | KDM4E (0.31) | MEN1KMT2AKDM4E | |
| SCHEMBL9494589 | 0.71 | NPC1 (0.45) | GAAMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL9494442 | 0.68 | NPC1 (0.40) | EPHX1EPHX2BCAT2GAAMEN1 | |
| SCHEMBL9495344 | 0.67 | TP53 (0.33) | EPHX1EPHX2GAAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |