Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513344 | 0.95 | MAPT (0.51) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL16217670 | 0.89 | MAPT (0.46) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL15131591 | 0.89 | ADRB2 (0.56) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL17929887 | 0.84 | PDCD1 (0.49) | SLC1A5MAPTPDCD1CD274PLA2G1B | |
| SCHEMBL14707364 | 0.84 | PDCD1 (0.61) | SLC1A5MAPTPDCD1CD274PLA2G1B | |
| SCHEMBL17929893 | 0.84 | PDCD1 (0.49) | SLC1A5MAPTPDCD1CD274PLA2G1B | |
| SCHEMBL3957408 | 0.81 | ALDH1A1 (0.53) | SLC1A5MAPTPLA2G1BATG4BADRB2 | |
| SCHEMBL24055108 | 0.81 | MAPT (0.49) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL24841040 | 0.81 | MAPT (0.40) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL17736343 | 0.80 | PDCD1 (0.60) | SLC1A5MAPTPDCD1CD274PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386198-B1 | THERMOCHROMIC MIXTURES | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-5188815-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1990002161-A1 | THERMOCHROMIC MIXTURES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-03-08 | — | — | WO | disclosed |