Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494095 | 0.95 | SLC1A5 (0.49) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL16217670 | 0.93 | MAPT (0.46) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL15131591 | 0.93 | ADRB2 (0.56) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL3957408 | 0.86 | ALDH1A1 (0.53) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL24055108 | 0.86 | MAPT (0.49) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL24841040 | 0.85 | MAPT (0.40) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL6370425 | 0.84 | MAPT (0.40) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL17929892 | 0.83 | ADRB2 (0.47) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL17929891 | 0.83 | ADRB2 (0.47) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL14947115 | 0.82 | ADRB2 (0.59) | MAPTPLA2G1BATG4BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386198-B1 | THERMOCHROMIC MIXTURES | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | claimed |