SCHEMBL949423

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL948501	0.92	SCD (0.46)	RPS6KA2NR1H2SCDSCD5
	SCHEMBL948462	0.89	NR1H2 (0.41)	RPS6KA2KDM4ENR1H2SCDSCD5
	SCHEMBL935471	0.84	RPS6KA3 (0.45)	RPS6KA2NR1H2SCDSCD5
	SCHEMBL949114	0.84	NR1H2 (0.43)	RPS6KA2NR1H2
	SCHEMBL936272	0.82	TAS2R8 (0.44)	—
	SCHEMBL935596	0.82	NR1H2 (0.39)	RPS6KA2NR1H2
	SCHEMBL948198	0.82	SCD (0.48)	RPS6KA2SCDSCD5
	SCHEMBL948520	0.81	SCD (0.45)	RPS6KA2SCDSCD5
	SCHEMBL12913234	0.81	SCD (0.36)	RPS6KA2SMN1; SMN2CYP2C19RAB9ANR1H2
	SCHEMBL948975	0.81	NR1H2 (0.47)	NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.