Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935011 | 0.93 | RPS6KA3 (0.34) | NR1H2RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL935471 | 0.92 | RPS6KA3 (0.45) | NR1H2RPS6KA3NR1H3RPS6KA2RPS6KA1 | |
| SCHEMBL935845 | 0.91 | RPS6KA3 (0.33) | NR1H2RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL936942 | 0.88 | RPS6KA3 (0.31) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1057502 | 0.87 | RPS6KA3 (0.31) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL935188 | 0.87 | DGAT1 (0.33) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL936272 | 0.86 | TAS2R8 (0.44) | — | |
| SCHEMBL949198 | 0.85 | RPS6KA2 (0.42) | NR1H2RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL948501 | 0.85 | SCD (0.46) | NR1H2RPS6KA3RPS6KA2 | |
| SCHEMBL12913263 | 0.84 | RPS6KA3 (0.38) | NR1H2RPS6KA3RPS6KA2RPS6KA1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010083-A1 | INDOLYL-PYRIDONE DERIVATIVES | VERNALIS (R & D) LTD (GB) | 2011-01-27 | — | — | WO | disclosed |