Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499116 | 0.88 | MAPT (0.32) | MEN1KMT2A | |
| SCHEMBL5253142 | 0.88 | MEN1 (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL9498421 | 0.80 | — | — | |
| SCHEMBL9497253 | 0.76 | MAPT (0.46) | MEN1KMT2A | |
| SCHEMBL9494438 | 0.74 | EPHX1 (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL9496918 | 0.73 | KMT2A (0.42) | MEN1KMT2A | |
| SCHEMBL9499230 | 0.73 | TSHR (0.39) | MEN1KMT2A | |
| SCHEMBL5252939 | 0.71 | RAB9A (0.45) | MEN1KMT2A | |
| SCHEMBL9494540 | 0.68 | KDM4E (0.31) | KDM4EMEN1KMT2A | |
| SCHEMBL9495361 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |