Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494535 | 0.88 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL9497253 | 0.87 | MAPT (0.46) | MAPTMEN1TP53POLBMAPK1 | |
| SCHEMBL9495344 | 0.77 | TP53 (0.33) | MAPTMEN1TP53POLBMAPK1 | |
| SCHEMBL5253142 | 0.76 | MEN1 (0.43) | MAPTMEN1TP53POLBMAPK1 | |
| SCHEMBL9498587 | 0.73 | CBS (0.41) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9494589 | 0.72 | NPC1 (0.45) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9496601 | 0.70 | TSHR (0.49) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9495470 | 0.69 | RAB9A (0.40) | MAPTMEN1TP53POLBMAPK1 | |
| SCHEMBL9495354 | 0.69 | HTT (0.44) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9499119 | 0.68 | MAPT (0.32) | MAPTMEN1TP53POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |