Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538803 | 0.77 | TERT (0.48) | TERTMAPTMEN1KMT2ALMNA | |
| SCHEMBL9494126 | 0.74 | MAPT (0.47) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL28470876 | 0.69 | TERT (0.49) | TERTMAPTMEN1KMT2ALMNA | |
| SCHEMBL4271584 | 0.65 | ALDH1A1 (0.67) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL21824248 | 0.64 | CFTR (0.48) | TERTMAPTMEN1KMT2ALMNA | |
| SCHEMBL10499745 | 0.64 | CFTR (0.39) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4408369 | 0.64 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1CYP1A2RAB9A | |
| SCHEMBL4268609 | 0.64 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1RAB9APTGFR | |
| SCHEMBL7165834 | 0.63 | TERT (0.43) | TERTMAPTMEN1KMT2AHTT | |
| SCHEMBL1821162 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179121-A | Pesticides | CIBA-GEIGY CORPORATION (US) | 1993-01-12 | — | — | US | claimed |
| US-5179121-A | Pesticides | CIBA-GEIGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |