Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494505 | 0.89 | KMT2A (0.46) | POLBFKBP1AKMT2AMEN1ATM | |
| SCHEMBL5257296 | 0.84 | MEN1 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9499235 | 0.82 | MEN1 (0.39) | POLBKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9495088 | 0.77 | RAB9A (0.47) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9494540 | 0.73 | KDM4E (0.31) | KMT2AMEN1 | |
| SCHEMBL9494592 | 0.72 | NPC1 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9496918 | 0.71 | KMT2A (0.42) | POLBFKBP1AKMT2AMEN1ATM | |
| SCHEMBL9495360 | 0.68 | HTT (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4795890 | 0.67 | KMT2A (0.66) | POLBKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL8106951 | 0.66 | KMT2A (0.62) | POLBKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |