Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644833 | 0.84 | KMT2A (0.46) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL9494682 | 0.83 | HSD11B1 (0.52) | HSD11B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9644758 | 0.79 | PTGES2 (0.40) | HSD11B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9644695 | 0.75 | HSD11B1 (0.69) | HSD11B1ALDH1A1KMT2APOLBCA2 | |
| SCHEMBL9644764 | 0.75 | HSD11B1 (0.69) | HSD11B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9721136 | 0.75 | HSD11B1 (0.45) | HSD11B1MEN1KMT2APOLBCA12 | |
| SCHEMBL28864502 | 0.75 | ALDH1A1 (0.60) | HSD11B1ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL29689874 | 0.73 | HSD11B1 (0.69) | HSD11B1ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL9644734 | 0.72 | HSD11B1 (0.59) | HSD11B1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL9721147 | 0.72 | RECQL (0.69) | HSD11B1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123953-A | DIHALOGENATED HERBICIDAL SULPHONES | RHONE-POULENC AGROCHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |