Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129229 | 0.77 | PTGS1 (0.53) | MGLLFAAHALDH1A1RAB9AHPGD | |
| SCHEMBL9181452 | 0.76 | CYP1A2 (0.40) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7128299 | 0.76 | SIGMAR1 (0.32) | — | |
| SCHEMBL1758179 | 0.74 | CYP1A2 (0.38) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL7626957 | 0.74 | LMNA (0.39) | LMNAPKMMAPK1PTGS1PTGS2 | |
| SCHEMBL1324992 | 0.73 | — | — | |
| SCHEMBL1324959 | 0.73 | — | — | |
| SCHEMBL25215380 | 0.73 | ACE (0.34) | — | |
| SCHEMBL13003189 | 0.73 | ELANE (0.37) | ALDH1A1RAB9AHPGDLMNATP53 | |
| SCHEMBL603323 | 0.72 | PTGS1 (0.47) | MGLLFAAHALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020239-A1 | METHODS FOR IN VIVO IMAGING OF CELLS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2155065-A1 | METHODS FOR IN VIVO IMAGING OF CELLS | The Johns Hopkins University (US) | 2010-02-24 | — | — | EP | disclosed |
| US-7517700-B2 | Colloidal metal particles having a coatings comprising noncross-linked, SH-activated dextran and derivative, used as detection reagents in immunology bioassays | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-04-14 | — | — | US | disclosed |
| WO-2008144028-A1 | METHODS FOR IN VIVO IMAGING OF CELLS | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080032421-A1 | Colloidal metal particles having a coatings comprising noncross-linked, SH-activated dextran and derivative, used as detection reagents in immunology bioassays | SLUKA PETER | 2008-02-07 | — | — | US | disclosed |
| US-7256054-B2 | Useful as detection reagents in immunoassays | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-20040038431-A1 | Useful as detection reagents in immunoassays | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2004-02-26 | — | — | US | disclosed |