SCHEMBL129229

SCHEMBL129229

O=C(CCCCCN1C(=O)C=CC1=O)C1CC(=O)N(O)C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.53
PTGS2 P35354 7/20 0.53
MGLL Q99685 7/20 0.47
FAAH O00519 5/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 2/20 0.47
RECQL P46063 2/20 0.47
RAB9A P51151 2/20 0.47
HSP90AA1 P07900 1/20 0.47
TLR9 Q9NR96 1/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
XBP1 P17861 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GPR35 Q9HC97 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674486 0.88 PTGS1 (0.39) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL29810264 0.79 GSK3A (0.38) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL27983508 0.78 PRKCA (0.46) FAAHALDH1A1HPGDHSP90AA1LMNA
SCHEMBL1935917 0.78 PRKCA (0.46) FAAHALDH1A1HPGDHSP90AA1LMNA
SCHEMBL949470 0.77 MGLL (0.50) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL6910643 0.77 PTGS1 (0.51) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL27309683 0.76 PRKCA (0.43) FAAHALDH1A1HPGDHSP90AA1LMNA
Ammonia Solution, Strong SCHEMBL28872308 0.75 PRKCA (0.42) FAAHALDH1A1HPGDHSP90AA1LMNA
SCHEMBL20621984 0.74 PTGS1 (0.58) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL8192444 0.73 LMNA (0.39) FAAHALDH1A1HPGDHSP90AA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240410900-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE HOFFMANN-LA ROCHE INC. (US) 2024-12-12 US claimed
EP-4388014-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2024-06-26 EP claimed
CN-117858905-A Multivalent anti-variant FC region antibodies and methods of use 豪夫迈·罗氏有限公司 2024-04-09 CN claimed
WO-2023021055-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2023-02-23 WO claimed
EP-1961767-B1 Diagnosis and treatment of cancers and other conditions BIOSCEPTRE INT LTD (AU) 2012-03-07 EP claimed
US-20110092674-A1 Non-Functional P2X7 Receptor INTREAT PTY LIMITED (AU) 2011-04-21 US claimed
US-20040142342-A1 Antibodies to non-functional P2X7 receptor diagnosis and treatment of cancers and other conditions INTREAT PTY LIMITED (AU) 2004-07-22 US claimed
EP-1360203-A1 ANTIBODIES TO NON-FUNCTIONAL P 2 X 7 RECEPTOR DIAGNOSIS AND TREATMENT OF CANCERS AND OTHER CONDITIONS Intreat Pty Limited (AU) 2003-11-12 EP claimed
WO-2003020762-A1 ANTIBODIES TO NON-FUNCTIONAL P2X7RECEPTOR, DIAGNOSIS AND TREATMENT OF CANCERS AND OTHER CONDITIONS INTREAT PTY LIMITED (AU) 2003-03-13 WO claimed
WO-2002057306-A1 ANTIBODIES TO NON-FUNCTIONAL P2X7 RECEPTOR DIAGNOSIS AND TREATMENT OF CANCERS AND OTHER CONDITIONS INTREAT PTY LIMITED (AU) 2002-07-25 WO claimed
EP-0624377-B1 Lysosomal enzyme-cleavable antitumor drug conjugates BRISTOL MYERS SQUIBB CO (US) 2002-01-23 EP claimed
US-6235886-B1 OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. 2001-05-22 US claimed
EP-0624377-A2 Lysosomal enzyme-cleavable antitumor drug conjugates Bristol-Myers Squibb Company (US) 1994-11-17 EP claimed
EP-0595863-A1 IMPLANT MATERIALS BRITISH TECHNOLOGY GROUP LTD (GB) 1994-05-11 EP claimed
WO-1993000935-A1 IMPLANT MATERIALS BRITISH TECHNOLOGY GROUP LTD. (GB) 1993-01-21 WO claimed
WO-2026097136-A1 IMMUNOGENIC COMPOSITION FOR PREVENTING OR TREATING GROUP A STREPTOCOCCUS INFECTION GRIFFITH UNIVERSITY (AU) 2026-05-15 WO disclosed
US-20240410900-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE HOFFMANN-LA ROCHE INC. (US) 2024-12-12 US disclosed
EP-0347959-A1 Antibodies against fibrin, immunogen used in their preparation, process for determining fibrin and pharmaceutical preparation based on the antibodies NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1989-12-27 EP disclosed
EP-0344578-A1 Method to determine an immunologically detectable substance, and suitable reaction vial for this Roche Diagnostics GmbH (DE) 1989-12-06 EP disclosed
EP-0329994-A1 Immunogen and its use in preparing antibodies to haemoglobin A1C Roche Diagnostics GmbH (DE) 1989-08-30 EP disclosed