Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492049 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9493024 | 0.82 | LMNA (0.40) | ALDH1A1 | |
| SCHEMBL9618232 | 0.74 | — | — | |
| SCHEMBL11097940 | 0.73 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL10881231 | 0.71 | LMNA (0.39) | ALDH1A1 | |
| SCHEMBL9493987 | 0.71 | — | — | |
| SCHEMBL29378248 | 0.71 | — | — | |
| SCHEMBL9492279 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL11203336 | 0.71 | — | — | |
| SCHEMBL9492962 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | claimed |
| US-5177091-A | Rheumatic disorders | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |