Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493879 | 0.83 | LMNA (0.39) | ALOX15LMNATSHRCHRM2CHRM4 | |
| SCHEMBL29728550 | 0.83 | LMNA (0.48) | ALOX15LMNATSHRCHRM2CHRM4 | |
| SCHEMBL1470236 | 0.81 | LMNA (0.39) | LMNATSHRGABRPGABRDGABRA1 | |
| SCHEMBL9494957 | 0.81 | LMNA (0.38) | ALOX15LMNATSHRCHRM2CHRM4 | |
| SCHEMBL9494655 | 0.79 | EPHX1 (0.38) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL608446 | 0.79 | — | — | |
| SCHEMBL15135759 | 0.79 | LMNA (0.38) | LMNACHRM1CHRM3GABRPGABRD | |
| SCHEMBL1469987 | 0.77 | LMNA (0.36) | LMNATHRBCA1CA2 | |
| SCHEMBL30949855 | 0.76 | — | — | |
| SCHEMBL1470091 | 0.76 | ALDH1A1 (0.50) | ALOX15LMNAMAPTHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179223-A | Reacting primary amine, urea and oxime | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |