Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494086 | 0.88 | CISD2 (0.39) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9496610 | 0.71 | MAPT (0.47) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL9494505 | 0.69 | KMT2A (0.46) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9495470 | 0.68 | RAB9A (0.40) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL9495088 | 0.68 | RAB9A (0.47) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL2091371 | 0.64 | MEN1 (0.71) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL11648308 | 0.63 | — | — | |
| Fluoride SCHEMBL11786773 | 0.63 | MEN1 (0.69) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL27915137 | 0.62 | MEN1 (0.44) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL9850862 | 0.62 | GAA (0.65) | RAB9AMEN1KMT2ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |