Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057528 | 0.84 | F2 (0.60) | PLATF2F10PLAUKAT6A | |
| SCHEMBL3419341 | 0.84 | F2 (0.60) | PLATF2F10PLAUKAT6A | |
| SCHEMBL9710933 | 0.83 | CTSS (0.56) | PLATCTSSF2F10PLAU | |
| SCHEMBL8743768 | 0.82 | CASP1 (0.51) | F2F10NPY5RMMEMMP2 | |
| SCHEMBL9664068 | 0.82 | F10 (0.71) | PLATF2F10PLAUTMPRSS6 | |
| SCHEMBL9665279 | 0.81 | PLAT (0.58) | PLATCTSSF2F10PLAU | |
| SCHEMBL8743773 | 0.79 | F2 (0.52) | PLATCTSSF2F10PLAU | |
| SCHEMBL3310154 | 0.78 | MMP2 (0.71) | F2NPY5RPOLBALDH1A1MMP2 | |
| SCHEMBL7290941 | 0.78 | MMP2 (0.71) | F2NPY5RPOLBALDH1A1MMP2 | |
| SCHEMBL31086814 | 0.78 | MMP2 (0.71) | F2NPY5RPOLBALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187102-A | Treating blood sample with thrombin inhibitor which does not bind bivalent cations | PENTAPHARM AG (CH) | 1993-02-16 | — | — | US | disclosed |