SCHEMBL9495646

SCHEMBL9495646

CN(C)C(=O)Sc1ccc(C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ALDH1A1 P00352 1/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
EPHX2 P34913 1/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
LIPE Q05469 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SRD5A2 P31213 1/20 0.39
TP53 P04637 1/20 0.38
GSK3B P49841 2/20 0.38
CYP1A2 P05177 1/20 0.38
PTPN1 P18031 1/20 0.38
LSS P48449 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20244667 0.84 ALDH1A1 (0.53) ALDH1A1NPC1RAB9AACHE
SCHEMBL11327104 0.83 ALDH1A1 (0.47) ALDH1A1NPC1RAB9AEPHX2SRD5A2
SCHEMBL13210509 0.83 NR1H3 (0.43) ALDH1A1
SCHEMBL9351813 0.81 CES2 (0.44) CES2ALDH1A1TP53
SCHEMBL11344976 0.80 TP53 (0.51) CES2ALDH1A1SLC6A2SLC6A4TP53
SCHEMBL7462058 0.79 LIPE (0.46) ALDH1A1RAB9ALIPE
SCHEMBL11337393 0.79 ALDH1A1 (0.46) CES2CES1ALDH1A1NPC1RAB9A
SCHEMBL20814566 0.78 ALDH1A1 (0.49) ALDH1A1RAB9ABCHEACHELIPE
SCHEMBL2256481 0.77 ALDH1A1 (0.47) ALDH1A1NPC1RAB9A
SCHEMBL16089507 0.77 ALDH1A1 (0.40) ALDH1A1ACHESLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1024801-C Process for preparing beta-D-phenyl-thioxylosides and their use FOURNIER INNOVATION SYNERGIE (FR) 1994-06-01 CN disclosed
US-5246961-A Venous antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1993-09-21 US disclosed
US-5101048-A Antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1992-03-31 US disclosed
CN-1041948-A New this glucosides of B-D-phenyl sulfo-and preparation method thereof and therepic use FOURNIER INNOVATION SYNERGIE (FR) 1990-05-09 CN disclosed