Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15729926 | 0.81 | — | — | |
| SCHEMBL15729928 | 0.81 | — | — | |
| SCHEMBL9741204 | 0.78 | — | — | |
| SCHEMBL1088366 | 0.73 | CYP3A4 (0.39) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL10390914 | 0.72 | LMNA (0.46) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL408176 | 0.72 | TSHR (0.46) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| Hydrochloric Acid SCHEMBL440466 | 0.71 | TSHR (0.45) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| Piperazine SCHEMBL27952191 | 0.70 | LMNA (0.33) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL13162564 | 0.69 | GABRA1 (0.52) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL106762 | 0.68 | GABRA1 (1.00) | LMNACYP3A4GABRA1TSHRGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243034-A | Disazo dyestuffs having a triazine moiety and a fiberreactive group of vinylsulfone series | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| US-5138041-A | Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |