Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714560 | 0.88 | POLB (0.70) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL9714565 | 0.88 | POLB (0.70) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10718940 | 0.87 | CYP3A4 (0.56) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9651998 | 0.83 | RAB9A (0.46) | POLBCYP3A4CYP2C9ABCB1HPGD | |
| SCHEMBL9652003 | 0.83 | RAB9A (0.43) | POLBCYP3A4CYP2C9ABCB1HPGD | |
| SCHEMBL10747617 | 0.83 | ABCB1 (0.46) | ABCB1 | |
| SCHEMBL5056904 | 0.83 | CYP3A4 (0.52) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10720252 | 0.83 | ABCB1 (0.68) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10722388 | 0.81 | CYP3A4 (0.53) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10718355 | 0.81 | CYP3A4 (0.53) | POLBCYP3A4CYP2C9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237099-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |