Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652003 | 0.90 | RAB9A (0.43) | RAB9ATSHRHPGDNPC1CYP3A4 | |
| SCHEMBL9496544 | 0.83 | POLB (0.51) | HPGDCYP3A4CYP2C9POLBSMN1; SMN2 | |
| SCHEMBL8172543 | 0.80 | POLB (0.68) | RAB9ATSHRNPC1CYP3A4CYP2C9 | |
| SCHEMBL9714565 | 0.79 | POLB (0.70) | CYP3A4CYP2C9POLB | |
| SCHEMBL9651949 | 0.78 | NPC1 (0.58) | RAB9ATSHRHPGDNPC1CYP3A4 | |
| SCHEMBL9651986 | 0.78 | ABCB1 (0.65) | CYP3A4CYP2C9POLBALDH1A1MEN1 | |
| SCHEMBL9651939 | 0.77 | RAB9A (0.57) | RAB9ATSHRHPGDNPC1CYP3A4 | |
| SCHEMBL8180270 | 0.75 | POLB (0.68) | RAB9ANPC1CYP3A4CYP2C9POLB | |
| SCHEMBL9651153 | 0.74 | MAPT (0.60) | HPGDCYP3A4CYP2C9POLBMEN1 | |
| SCHEMBL9714560 | 0.73 | POLB (0.70) | CYP3A4CYP2C9POLBSMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261755-B1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |