Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703014 | 0.74 | KMT2A (0.52) | LMNARAPGEF4HTTKMT2ANPSR1 | |
| SCHEMBL9496309 | 0.72 | FABP4 (0.49) | LMNAHTTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2047218 | 0.72 | RAPGEF4 (0.67) | LMNARAPGEF4HTTNPSR1ALDH1A1 | |
| SCHEMBL7595633 | 0.70 | LMNA (0.74) | LMNAHTTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL18184378 | 0.69 | — | — | |
| SCHEMBL5371744 | 0.66 | RAPGEF4 (0.44) | LMNARAPGEF4HTTKMT2ANPSR1 | |
| SCHEMBL4735410 | 0.66 | RAPGEF4 (0.44) | LMNARAPGEF4HTTKMT2AALDH1A1 | |
| SCHEMBL10601772 | 0.66 | RAPGEF4 (0.44) | LMNARAPGEF4HTTKMT2ANPSR1 | |
| SCHEMBL1112185 | 0.65 | — | — | |
| SCHEMBL5508609 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061761-B1 | A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE | Baker Instruments Corporation (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0061761-A1 | A method for preparing a mononucleotide-3'-phosphodiester-based substrate | Baker Instruments Corporation (US) | 1982-10-06 | — | — | EP | claimed |
| EP-0331032-B1 | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5032680-A | Antitumor | KURARAY CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0138559-B1 | KETOALKYLPHOSPHOLIPIDS AND THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0225129-B1 | PHOSPHOLIPID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0184905-B1 | 2-ACETOACETYLGLYCEROL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4778912-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0061761-B1 | A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE | Baker Instruments Corporation (US) | 1988-05-18 | — | — | EP | disclosed |
| EP-0061760-B1 | A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE | Baker Instruments Corporation (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4710579-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-01 | — | — | US | disclosed |
| US-4649203-A | ANTITUMOR, FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4605645-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0184905-A1 | 2-Acetoacetylglycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |
| US-4529796-A | Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity | BAKER INSTRUMENTS CORPORATION (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0081386-B1 | 5-FLUORO-2'-DEOXYURIDINE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | TEIJIN LIMITED (JP) | 1985-05-29 | — | — | EP | disclosed |
| EP-0138559-A2 | Ketoalkylphospholipids and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-24 | — | — | EP | disclosed |
| EP-0081386-A1 | 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof | TEIJIN LIMITED (JP) | 1983-06-15 | — | — | EP | disclosed |
| EP-0061760-A1 | A method for preparing a mononucleotide-3'-phosphodiester-based substrate | Baker Instruments Corporation (US) | 1982-10-06 | — | — | EP | disclosed |
| EP-0061761-A1 | A method for preparing a mononucleotide-3'-phosphodiester-based substrate | Baker Instruments Corporation (US) | 1982-10-06 | — | — | EP | disclosed |