Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494062 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9454924 | 0.87 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9494926 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9497035 | 0.84 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9454842 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9495525 | 0.79 | AGTR2 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9454851 | 0.78 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9454425 | 0.78 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709623 | 0.77 | AGTR1 (0.42) | AGTR1 | |
| Hydrochloric Acid SCHEMBL9495971 | 0.77 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236937-A | Treating hypertension, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-17 | — | — | US | disclosed |
| EP-0499415-A1 | Pyridine and quinoline derivatives, processes for their manufacture and their use as angiotensin II antagonists | ZENECA LIMITED (GB) | 1992-08-19 | — | — | EP | disclosed |