Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494067 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9494917 | 0.85 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9497028 | 0.84 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9454924 | 0.84 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9454842 | 0.77 | AGTR1 (0.43) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9495964 | 0.77 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9454851 | 0.75 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9454425 | 0.74 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9494062 | 0.74 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9709623 | 0.74 | AGTR1 (0.42) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236937-A | Treating hypertension, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-17 | — | — | US | disclosed |