SCHEMBL94971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30565215	0.85	PGR (0.75)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL1403074	0.85	PGR (0.75)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL1859217	0.84	PGR (0.68)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL22441735	0.84	PGR (0.72)	PGRBRD4HSD17B2PKMKDR
	SCHEMBL1489068	0.84	PGR (0.65)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL28121844	0.84	PKM (0.72)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL14433749	0.83	HSD17B2 (0.66)	PGRBRD4HSD17B2PKMMAP4K4
	SCHEMBL95092	0.81	KMT2A (0.68)	PGRPKMPTPN2PTPN1PTPN5
	SCHEMBL95797	0.81	PGR (0.65)	PGRPKMKDRAURKBPTPN2
	SCHEMBL97999	0.81	PGR (0.73)	PGRPKMKDRAURKBPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.