Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948843 | 0.92 | ESR2 (0.38) | S1PR1ESR2MIFHTR6 | |
| SCHEMBL14321088 | 0.81 | S1PR1 (0.44) | S1PR1S1PR4S1PR5 | |
| SCHEMBL2017781 | 0.81 | S1PR1 (0.44) | S1PR1S1PR4S1PR5 | |
| SCHEMBL946678 | 0.78 | S1PR1 (0.45) | S1PR1ESR2MIFHTR6 | |
| SCHEMBL948567 | 0.76 | NR1H2 (0.32) | — | |
| SCHEMBL948569 | 0.76 | NR1H2 (0.32) | — | |
| SCHEMBL949133 | 0.73 | S1PR1 (0.41) | S1PR1S1PR4S1PR5 | |
| SCHEMBL948764 | 0.69 | S1PR1 (0.63) | S1PR1S1PR4S1PR5 | |
| SCHEMBL2446502 | 0.69 | S1PR1 (0.46) | S1PR1MIFS1PR4S1PR5 | |
| SCHEMBL2446506 | 0.69 | S1PR1 (0.46) | S1PR1MIFS1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005295-A1 | MODULATORS OF THE SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |