Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP1 | O94782 | 13/20 | 0.38 |
| ▸ | WDR48 | Q8TAF3 | 10/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500363 | 0.88 | SMN1; SMN2 (0.38) | LMNAUSP1WDR48PIP4K2CNPC1 | |
| SCHEMBL9500599 | 0.86 | LMNA (0.39) | LMNAUSP1WDR48PIP4K2CTSHR | |
| SCHEMBL9498428 | 0.85 | RARB (0.40) | LMNAUSP1WDR48NPC1ALDH1A1 | |
| SCHEMBL9499138 | 0.84 | RARB (0.45) | LMNAUSP1WDR48NPC1ALDH1A1 | |
| SCHEMBL9498708 | 0.83 | RARB (0.47) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9500275 | 0.83 | RARB (0.47) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9498197 | 0.83 | RARB (0.47) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9498424 | 0.83 | RARB (0.47) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9502051 | 0.83 | RARB (0.47) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9498391 | 0.83 | LMNA (0.37) | LMNAUSP1WDR48NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |