Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 11/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498396 | 0.86 | LMNA (0.38) | LMNAPIP4K2CUSP1WDR48TSHR | |
| SCHEMBL9500246 | 0.84 | LMNA (0.37) | LMNAUSP1WDR48KMT2A | |
| SCHEMBL9498391 | 0.84 | LMNA (0.37) | LMNAUSP1WDR48KMT2ATSHR | |
| SCHEMBL9500363 | 0.83 | SMN1; SMN2 (0.38) | LMNAPIP4K2CUSP1WDR48 | |
| SCHEMBL9502022 | 0.81 | CCR1 (0.44) | LMNAKMT2A | |
| SCHEMBL9498428 | 0.81 | RARB (0.40) | LMNAUSP1WDR48KMT2ATSHR | |
| SCHEMBL9500576 | 0.81 | ALDH1A1 (0.39) | LMNAUSP1WDR48KMT2ATSHR | |
| SCHEMBL9499138 | 0.80 | RARB (0.45) | LMNAUSP1WDR48KMT2ATSHR | |
| SCHEMBL9498712 | 0.80 | NPC1 (0.40) | LMNAKMT2ATSHR | |
| SCHEMBL9500275 | 0.79 | RARB (0.47) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |