Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499138 | 0.96 | RARB (0.45) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9502051 | 0.95 | RARB (0.47) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9500275 | 0.95 | RARB (0.47) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9498708 | 0.95 | RARB (0.47) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9498424 | 0.95 | RARB (0.47) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9498197 | 0.95 | RARB (0.47) | RARBNFKB1LMNAKDM4EMEN1 | |
| SCHEMBL9500363 | 0.92 | SMN1; SMN2 (0.38) | RARBLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9498396 | 0.85 | LMNA (0.38) | LMNAALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL9500477 | 0.84 | RAB9A (0.52) | NFKB1LMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL9498712 | 0.82 | NPC1 (0.40) | LMNAKDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |