SCHEMBL9498495

SCHEMBL9498495

CC(O[N+](=O)[O-])C(=O)NCC(C)(C)CN

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL9795244 0.92
SCHEMBL9498615 0.84
SCHEMBL9501653 0.78 KMT2A (0.33)
SCHEMBL9497764 0.75 NOS1 (0.42)
SCHEMBL23173377 0.73 KDM4E (0.38) RENKDM4E
SCHEMBL9499500 0.73 MEN1 (0.41) RENKDM4E
SCHEMBL9499367 0.72 KDM4E (0.32) KDM4E
SCHEMBL9497845 0.70 ALDH1A1 (0.36) KDM4E
SCHEMBL9498647 0.69 HTT (0.40) KDM4E
Fumaric Acid SCHEMBL9795063 0.69 NOS1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367019-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS Roche Diagnostics GmbH (DE) 1993-05-12 EP disclosed
EP-0367019-A1 Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds Roche Diagnostics GmbH (DE) 1990-05-09 EP disclosed