Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500550 | 0.86 | PDK2 (0.44) | LMNAROCK2ROCK1PDE10AUSP1 | |
| SCHEMBL9501996 | 0.86 | LMNA (0.38) | LMNAROCK2ROCK1TSHRRECQL | |
| SCHEMBL9502130 | 0.84 | ROCK2 (0.38) | LMNAROCK2ROCK1GRM5CYP1A2 | |
| SCHEMBL9498247 | 0.83 | ALOX5AP (0.41) | LMNAHDAC8ROCK2ROCK1SCN9A | |
| SCHEMBL9499944 | 0.83 | LMNA (0.36) | LMNAROCK2ROCK1TSHRRECQL | |
| SCHEMBL9498645 | 0.83 | LMNA (0.38) | LMNAROCK2ROCK1TSHRRECQL | |
| SCHEMBL9500367 | 0.81 | ROCK2 (0.36) | LMNAROCK2ROCK1GRM5CTDSP1 | |
| SCHEMBL9500327 | 0.81 | BRS3 (0.35) | LMNAROCK2ROCK1GABRPGABRD | |
| SCHEMBL9500391 | 0.80 | LMNA (0.36) | LMNAROCK2ROCK1 | |
| SCHEMBL9500781 | 0.80 | MAPT (0.42) | LMNAROCK2ROCK1SCN9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |