Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 10/20 | 0.41 |
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500835 | 0.92 | ECE1 (0.41) | CTRB1TRPM8ECE1KDM1AMAOA | |
| SCHEMBL9500880 | 0.92 | CYP3A4 (0.42) | CTRB1TRPM8ECE1KDM1AMAOA | |
| SCHEMBL9499459 | 0.92 | CYP3A4 (0.42) | CTRB1TRPM8ECE1KDM1AMAOA | |
| SCHEMBL9502325 | 0.89 | CYP3A4 (0.42) | CTRB1TRPM8ECE1KDM1AMAOA | |
| SCHEMBL9498809 | 0.86 | CYP3A4 (0.43) | TRPM8KDM1AMAOACYP3A4TSHR | |
| SCHEMBL9499490 | 0.85 | CYP3A4 (0.43) | CTRB1TRPM8ECE1KDM1AMAOA | |
| SCHEMBL9500504 | 0.81 | CYP3A4 (0.47) | TRPM8KDM1AMAOACYP3A4TSHR | |
| SCHEMBL9633645 | 0.75 | TRPM8 (0.60) | CTRB1TRPM8ECE1CTSLCTSB | |
| SCHEMBL9633246 | 0.75 | TRPM8 (0.60) | CTRB1TRPM8ECE1CTSLCTSB | |
| SCHEMBL8545295 | 0.75 | TRPM8 (0.60) | CTRB1TRPM8ECE1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5145872-A | PEPTIDES WITH PHARMACEUTICAL ACTIVITY | ZAMBON GROUP, S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| EP-0333000-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |