Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498764 | 0.92 | CTRB1 (0.44) | ECE1TRPM8CYP3A4TSHRKDM1A | |
| SCHEMBL9499459 | 0.88 | CYP3A4 (0.42) | ECE1TRPM8CYP3A4TSHRKDM1A | |
| SCHEMBL9500880 | 0.88 | CYP3A4 (0.42) | ECE1TRPM8CYP3A4TSHRKDM1A | |
| SCHEMBL9502325 | 0.85 | CYP3A4 (0.42) | ECE1TRPM8CYP3A4TSHRKDM1A | |
| SCHEMBL9498809 | 0.83 | CYP3A4 (0.43) | TRPM8CYP3A4TSHRKDM1AALDH1A1 | |
| SCHEMBL9499490 | 0.82 | CYP3A4 (0.43) | ECE1TRPM8CYP3A4TSHRKDM1A | |
| SCHEMBL9500824 | 0.79 | CTSB (0.43) | ECE1TRPM8CYP3A4TSHRALDH1A1 | |
| SCHEMBL9502247 | 0.78 | TRPM8 (0.54) | TRPM8ALDH1A1CTRB1TOP2ATOP2B | |
| SCHEMBL9512731 | 0.78 | TRPM8 (0.54) | TRPM8ALDH1A1CTRB1TOP2ATOP2B | |
| SCHEMBL9500504 | 0.78 | CYP3A4 (0.47) | TRPM8CYP3A4TSHRKDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5145872-A | PEPTIDES WITH PHARMACEUTICAL ACTIVITY | ZAMBON GROUP, S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| EP-0333000-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |