Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487749 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2TP53HTT | |
| SCHEMBL2187863 | 0.75 | SELL (0.48) | ALDH1A1TDP1SMN1; SMN2MAPTSELL | |
| SCHEMBL8578465 | 0.74 | TSHR (0.50) | ALDH1A1TDP1SMN1; SMN2MAPTSELL | |
| SCHEMBL7693503 | 0.73 | SELL (0.57) | ALDH1A1TDP1SMN1; SMN2HTTMEN1 | |
| SCHEMBL10487714 | 0.73 | MCL1 (0.42) | ALDH1A1TDP1SMN1; SMN2TP53HTT | |
| SCHEMBL30309481 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2TP53HTT | |
| SCHEMBL9500842 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TDP1SMN1; SMN2TP53HTT | |
| SCHEMBL2057086 | 0.72 | TSHR (0.53) | ALDH1A1TDP1SMN1; SMN2MEN1MAPT | |
| SCHEMBL2057084 | 0.72 | TSHR (0.53) | ALDH1A1TDP1SMN1; SMN2MEN1MAPT | |
| SCHEMBL2010317 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | claimed |
| US-5101069-A | PROCESS FOR THE PREPARATION OF HYDROXYETHYLSULFONYLNITRO- AND HYDROXYETHYLSULFONYLAMINO-BENZOIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-4960929-A | Chemical intermediate for making fiber reactive azo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |