SCHEMBL9499016

SCHEMBL9499016

c1ccc(Cc2ccc(C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.60
LTA4H P09960 2/20 0.46
SLC6A2 P23975 3/20 0.46
SLC6A4 P31645 3/20 0.46
SLC6A3 Q01959 3/20 0.46
IDH1 O75874 1/20 0.45
PLA2G10 O15496 1/20 0.43
PLA2G2A P14555 1/20 0.43
LMNA P02545 1/20 0.43
SLC22A2 O15244 1/20 0.42
CFTR P13569 1/20 0.41
GOPC Q9HD26 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL11228811 0.82 CALM1 (0.50) CALM1LTA4HSLC6A2SLC6A4SLC6A3
SCHEMBL3357456 0.81 CALM1 (0.55) CALM1LTA4HSLC6A2SLC6A4SLC6A3
SCHEMBL8767137 0.81 CALM1 (0.55) CALM1LTA4HSLC6A2SLC6A4SLC6A3
SCHEMBL3360010 0.81 CALM1 (0.55) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL13496520 0.81 CALM1 (0.55) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL8094422 0.81 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL2956444 0.81 SLC6A2 (0.63) SLC6A2SLC6A4SLC6A3CFTRGOPC
SCHEMBL972712 0.81 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL6895362 0.79 CALM1 (0.52) CALM1LTA4HSLC6A2SLC6A4SLC6A3
SCHEMBL14361867 0.78 TP53 (0.59) SLC6A2SLC6A4SLC6A3LMNACFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384818-B1 COMPOSITIONS BASED ON POLYPHENYL METHANES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DIELECTRICUMS ELF ATOCHEM S.A. (FR) 1993-09-01 EP disclosed
US-5200385-A Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness RICOH COMPANY, LTD. (JP) 1993-04-06 US disclosed
US-5192463-A Reaction of chlorine with toluene to form benzylidene chloride and reaction with inorganic halide for dielectrics ATOCHEM (FR) 1993-03-09 US disclosed
US-5126486-A Color developers for leuco dyes in thermal printing RICOH COMPANY, LTD. (JP) 1992-06-30 US disclosed
US-5043313-A Mixture of leuco dye and diphenyl polyhydroxy sulfone compound RICOH COMPANY, LTD. (JP) 1991-08-27 US disclosed
US-4978651-A With a colorless or light colored leuco dye for inducing color formation RICOH COMPANY, LTD. (JP) 1990-12-18 US disclosed