Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752526 | 0.79 | SMN1; SMN2 (0.46) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL30087171 | 0.79 | LMNA (0.60) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL19555758 | 0.79 | SMN1; SMN2 (0.46) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL9190288 | 0.79 | WDR5 (0.62) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL15114753 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1LMNASMN1; SMN2DAO | |
| SCHEMBL9500592 | 0.76 | MAPT (0.47) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1269571 | 0.75 | MCL1 (0.56) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL10970442 | 0.75 | MCL1 (0.51) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL118785 | 0.73 | MCL1 (0.72) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 | |
| SCHEMBL7413146 | 0.73 | MCL1 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |