Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481181 | 0.80 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3672075 | 0.79 | WDR5 (0.71) | MAPTKMT2AMAOBAOC3LMNA | |
| SCHEMBL9499135 | 0.76 | KDM4E (0.48) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2778615 | 0.76 | CA12 (0.52) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12061812 | 0.75 | GAA (0.66) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4947908 | 0.75 | LMNA (0.56) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL656832 | 0.72 | LMNA (0.67) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11130288 | 0.72 | GAA (0.58) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10858118 | 0.72 | LMNA (0.58) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1072731 | 0.72 | GPR174 (0.51) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |