Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498680 | 0.84 | NPC1 (0.41) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL20018787 | 0.83 | CCR1 (0.46) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL9499159 | 0.82 | MAPT (0.38) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9500599 | 0.81 | LMNA (0.39) | LMNAKMT2A | |
| SCHEMBL9499176 | 0.81 | SMN1; SMN2 (0.44) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9498220 | 0.81 | CYP11B1 (0.38) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5427650 | 0.80 | KDM4E (0.42) | CCR1CCR5CCR8LMNANPC1 | |
| SCHEMBL9500477 | 0.79 | RAB9A (0.52) | CYP3A4LMNANPC1TP53RAB9A | |
| SCHEMBL9500172 | 0.79 | CYP2D6 (0.40) | CYP3A4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9498372 | 0.79 | CYP4F2 (0.38) | LMNANPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |