Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499306 | 1.00 | CTSS (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9496752 | 0.94 | PPARG (0.47) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9496746 | 0.94 | PPARG (0.47) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9501559 | 0.94 | CTSS (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9501550 | 0.94 | CTSS (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9498132 | 0.91 | OPRM1 (0.49) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9498146 | 0.91 | OPRM1 (0.49) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9496833 | 0.91 | CTSK (0.53) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL23154872 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL30999386 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216124-A | Analgesics | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |