Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500522 | 1.00 | KCNH2 (0.40) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9500323 | 1.00 | KCNH2 (0.40) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9500222 | 1.00 | KCNH2 (0.40) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9498670 | 1.00 | KCNH2 (0.40) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9500482 | 0.99 | KCNH2 (0.37) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9502015 | 0.95 | GABRP (0.38) | — | |
| SCHEMBL9500391 | 0.89 | LMNA (0.36) | SMN1; SMN2GAAGCGR | |
| SCHEMBL9498342 | 0.87 | KCNH2 (0.36) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9498235 | 0.87 | KCNH2 (0.36) | KCNH2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9498645 | 0.83 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |