Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500522 | 0.99 | KCNH2 (0.40) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9498670 | 0.99 | KCNH2 (0.40) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9500222 | 0.99 | KCNH2 (0.40) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9500323 | 0.99 | KCNH2 (0.40) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9499377 | 0.99 | KCNH2 (0.40) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9502015 | 0.96 | GABRP (0.38) | GABRPGABRDGABRA1IDO1GABRB1 | |
| SCHEMBL9500391 | 0.90 | LMNA (0.36) | GCGRSMN1; SMN2 | |
| SCHEMBL9498342 | 0.85 | KCNH2 (0.36) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9498235 | 0.85 | KCNH2 (0.36) | KCNH2GCGRMAPTRAB9ANPC1 | |
| SCHEMBL9498645 | 0.84 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |