Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 7/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501405 | 0.90 | KMT2A (0.41) | EPHX2PPARGMRGPRX1KMT2AHTT | |
| SCHEMBL9501500 | 0.89 | EPHX2 (0.38) | EPHX2PPARGMRGPRX1JAK1BRAF | |
| SCHEMBL9367139 | 0.88 | KMT2A (0.35) | EPHX2PPARGMRGPRX1BRAFKMT2A | |
| SCHEMBL9502941 | 0.81 | GAA (0.40) | EPHX2PPARGMRGPRX1JAK1BRAF | |
| SCHEMBL9363636 | 0.81 | KMT2A (0.37) | EPHX2PPARGMRGPRX1BRAFKMT2A | |
| SCHEMBL9499704 | 0.81 | ULK1 (0.37) | MRGPRX1BRAFKMT2AHTTKDM4E | |
| SCHEMBL9368768 | 0.80 | NPC1 (0.40) | EPHX2PPARGMRGPRX1JAK1KMT2A | |
| SCHEMBL9502967 | 0.79 | KMT2A (0.43) | EPHX2PPARGMRGPRX1KMT2AHTT | |
| SCHEMBL9499692 | 0.79 | TSHR (0.44) | EPHX2PPARGMRGPRX1KMT2AKDM4E | |
| SCHEMBL9364420 | 0.79 | CA12 (0.38) | MRGPRX1BRAFKMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |