SCHEMBL9499892

SCHEMBL9499892

CN(C)c1ccccc1.COc1ccc(C)cc1N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
CYP3A4 P08684 1/20 0.68
SLC6A4 P31645 3/20 0.48
ACHE P22303 1/20 0.44
ADRA2B P18089 1/20 0.44
PTGS1 P23219 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SLC6A2 P23975 2/20 0.43
SLC6A3 Q01959 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
GAA P10253 1/20 0.42
TSHR P16473 2/20 0.42
APP P05067 1/20 0.41
GPR35 Q9HC97 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
NQO2 P16083 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495045 0.82 ALDH1A1 (1.00) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
SCHEMBL55544 0.82 ALDH1A1 (1.00) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
Hydrochloric Acid SCHEMBL10706930 0.80 ALDH1A1 (0.95) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
SCHEMBL10208072 0.77 ALDH1A1 (0.55) ALDH1A1CYP3A4ADRA2BPTGS1TDP1
2,5-Xylidine SCHEMBL9308900 0.75 ALDH1A1 (0.84) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
SCHEMBL11993859 0.75 ALDH1A1 (0.69) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
Orthocresol SCHEMBL11881671 0.74 ALDH1A1 (0.68) ALDH1A1CYP3A4SLC6A4ACHEADRA2B
Sulfuric Acid SCHEMBL10957580 0.73 ALDH1A1 (0.78) ALDH1A1CYP3A4ACHETDP1MEN1
SCHEMBL7883774 0.71 ACHE (0.48) ALDH1A1CYP3A4ACHETDP1MEN1
SCHEMBL11354738 0.71 ALDH1A1 (0.75) ALDH1A1CYP3A4SLC6A4ACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0373110-B1 PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL CIBA-GEIGY AG (CH) 1993-04-21 EP disclosed
EP-0373110-A2 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1990-06-13 EP disclosed