Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424270 | 0.72 | CHRNA7 (0.44) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL21573624 | 0.72 | CHRNA7 (0.42) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL14027182 | 0.72 | CHRNA7 (0.42) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL26462625 | 0.71 | GNAI3 (0.41) | CHRM2CHRM1 | |
| SCHEMBL7416179 | 0.69 | CHRNA7 (0.41) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7362613 | 0.68 | CHRNA7 (0.35) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL7323705 | 0.68 | CHRNA7 (0.35) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL10915261 | 0.67 | CHRNA7 (0.42) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL415807 | 0.67 | CHRNA7 (0.42) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 | |
| SCHEMBL22776221 | 0.67 | CHRNA7 (0.42) | CHRNA4CHRNB2CHRNA7CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370415-B1 | QUINUCLIDINES, THEIR PHARMACEUTICAL USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM KG (DE) | 1993-06-02 | — | — | EP | claimed |
| EP-0370415-A1 | Quinuclidines, their pharmaceutical use and process for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1990-05-30 | — | — | EP | claimed |