Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499593 | 0.91 | HTR6 (0.65) | HTR6MTNR1AMTNR1B | |
| SCHEMBL1567238 | 0.86 | MTNR1A (0.55) | HTR6MTNR1AMTNR1BPRMT5WDR77 | |
| SCHEMBL1567241 | 0.86 | MTNR1A (0.55) | HTR6MTNR1AMTNR1BOPRM1 | |
| SCHEMBL16130554 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL12964162 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1B | |
| SCHEMBL24105927 | 0.81 | MTNR1A (0.53) | MTNR1AMTNR1BPRMT5WDR77OPRM1 | |
| SCHEMBL4714587 | 0.79 | HTR6 (0.51) | HTR6MTNR1AMTNR1BPRMT5WDR77 | |
| SCHEMBL6184833 | 0.79 | HTR6 (0.51) | HTR6MTNR1AMTNR1BPRMT5WDR77 | |
| SCHEMBL21471468 | 0.79 | MTNR1A (0.54) | HTR6MTNR1AMTNR1BHTR2C | |
| SCHEMBL4020562 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |