Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.65 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499994 | 0.91 | HTR6 (0.54) | HTR6MTNR1AMTNR1B | |
| SCHEMBL1568036 | 0.87 | KDM4C (0.53) | HTR6KDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL12428550 | 0.85 | HTR6 (0.49) | HTR6KDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL30572310 | 0.80 | BLM (0.50) | KDM4CKDM5AKDM5BALDH1A1HTT | |
| SCHEMBL1725811 | 0.80 | BLM (0.50) | KDM4CKDM5AKDM5BALDH1A1HTT | |
| SCHEMBL315083 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL316069 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL20662842 | 0.79 | TAS1R3 (0.64) | HTR6KDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL1567238 | 0.77 | MTNR1A (0.55) | HTR6KDM4CKDM5AKDM5BMTNR1A | |
| SCHEMBL1567241 | 0.77 | MTNR1A (0.55) | HTR6KDM4CKDM5AKDM5BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |