SCHEMBL95001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6069080	0.84	ALDH1A1 (0.51)	ALDH1A1HPGDLMNAACHESLC22A2
	SCHEMBL26814869	0.84	HPGD (0.67)	ALDH1A1HPGDLMNAACHESLC22A2
	SCHEMBL1512850	0.84	ALDH1A1 (0.51)	ALDH1A1HPGDLMNAACHESLC22A2
	SCHEMBL28562969	0.84	ALDH1A1 (0.56)	ALDH1A1HPGDLMNAACHESMN1; SMN2
	SCHEMBL15209143	0.82	ALDH1A1 (0.63)	ALDH1A1HPGDLMNAACHESLC22A2
	SCHEMBL11441548	0.82	NPC1 (0.63)	ALDH1A1HPGDNFKB1SMN1; SMN2NPC1
	SCHEMBL13566308	0.82	ALDH1A1 (0.47)	ALDH1A1HPGDLMNAACHESLC22A2
	SCHEMBL10644293	0.80	SMN1; SMN2 (0.59)	ALDH1A1HPGDLMNATSHRSMN1; SMN2
	Bromide SCHEMBL10648617	0.79	SMN1; SMN2 (0.57)	ALDH1A1LMNATSHRSMN1; SMN2
	SCHEMBL7214868	0.77	THRA (0.64)	ALDH1A1SMN1; SMN2NPC1RAB9ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.