Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323561 | 0.88 | F10 (0.44) | LMNACA1CA2F12TSHR | |
| Trifluoroacetic Acid SCHEMBL13269478 | 0.85 | KLK1 (0.50) | LMNACA1CA2F12TSHR | |
| SCHEMBL27242081 | 0.83 | LMNA (0.50) | LMNAF12TSHRHSD17B10PRSS1 | |
| SCHEMBL10436207 | 0.82 | LMNA (0.54) | LMNAF12TSHRPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL11798099 | 0.80 | LMNA (0.58) | LMNAF12TSHRPRSS1PRSS3 | |
| SCHEMBL17134224 | 0.80 | CA2 (0.52) | LMNACA1CA2TSHRHSD17B10 | |
| SCHEMBL9314470 | 0.79 | LMNA (0.54) | LMNACA1CA2F12HSD17B10 | |
| SCHEMBL1786932 | 0.78 | LCK (0.53) | LMNACA1CA2TSHRHSD17B10 | |
| SCHEMBL30765123 | 0.78 | LCK (0.53) | LMNACA1CA2TSHRHSD17B10 | |
| SCHEMBL19523347 | 0.78 | SMN1; SMN2 (0.53) | LMNACA1CA2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150313889-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2015-11-05 | — | — | US | disclosed |
| US-20150313889-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2015-11-05 | — | — | US | disclosed |
| US-9115107-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-9115107-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20150011511-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20150011511-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-8877805-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8877805-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20140080790-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140080790-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-0535037-A1 | HYBRID PLASMINOGEN ACTIVATORS | BEECHAM GROUP PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1991019793-A2 | HYBRID PLASMINOGEN ACTIVATORS | BEECHAM GROUP PLC (GB) | 1991-12-26 | — | — | WO | disclosed |
| EP-0283563-B1 | NOVEL DERIVATIVES | BEECHAM GROUP PLC (GB) | 1991-05-29 | — | — | EP | disclosed |
| EP-0155388-B1 | ENZYME-PROTEIN CONJUGATE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL USE THEREOF | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |
| EP-0283563-A2 | Novel derivatives | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |
| US-4741903-A | Novel enzyne derivatives | BEECHAM GROUP P.L.C. (GB) | 1988-05-03 | — | — | US | disclosed |
| US-4730050-A | Novel enzyme derivatives | BEECHAM GROUP P.L.C. (GB) | 1988-03-08 | — | — | US | disclosed |
| US-4600580-A | Novel enzyme derivatives | BEECHAM GROUP P.L.C. (GB) | 1986-07-15 | — | — | US | disclosed |
| EP-0184363-A2 | Enzyme conjugates and their therapeutical use | BEECHAM GROUP PLC (GB) | 1986-06-11 | — | — | EP | disclosed |
| EP-0155388-A2 | Enzyme-protein conjugate, process for its preparation and pharmaceutical use thereof | BEECHAM GROUP PLC (GB) | 1985-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080790-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | DPP4, DPP9, DPP7 | LMNA 2175/4885CA1 1650/4885CA2 1208/4885 |
| US-20150011511-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | DPP4, DPP9, DPP7 | LMNA 2175/4885CA1 1650/4885CA2 1208/4885 |
| US-20150313889-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | DPP4, DPP9, DPP7 | LMNA 2175/4885CA1 1650/4885CA2 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.