Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624861 | 0.82 | HPGD (0.46) | RHEBKDM4ENPSR1MAPTALDH1A1 | |
| SCHEMBL2423602 | 0.78 | — | — | |
| SCHEMBL16581363 | 0.76 | SIRT1 (0.43) | LMNAKDM4EL3MBTL1MAPTDHFR | |
| SCHEMBL467564 | 0.76 | HAO1 (0.40) | HAO1L3MBTL1ALDH1A1TSHRTDP1 | |
| SCHEMBL6639826 | 0.76 | P4HB (0.35) | LMNAKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9497761 | 0.76 | LMNA (0.40) | LMNALDHA | |
| SCHEMBL11141938 | 0.76 | HAO1 (0.40) | HAO1LMNALDHANOTUM | |
| SCHEMBL16581613 | 0.76 | POLB (0.33) | ALDH1A1KMT2AHTT | |
| SCHEMBL6915666 | 0.75 | RHEB (0.55) | HAO1RHEBPKMLMNAKDM4E | |
| SCHEMBL29543966 | 0.75 | RHEB (0.55) | HAO1RHEBPKMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622470-B | A kind of preparation method of sulfur-bearing indenone or derivatives thereof | 温州大学 | 2017-11-28 | — | — | CN | disclosed |
| CN-105622470-A | Method for preparing sulfur containing indenone or derivatives thereof | UNIV WENZHOU | 2016-06-01 | — | — | CN | disclosed |
| EP-0351332-B1 | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0351332-A1 | Herbicidal compounds and compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1990-01-17 | — | — | EP | disclosed |
| US-4414210-A | 2-Hydroxyarylethyltriazole fungicides | ROHM AND HAAS COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |