Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392834 | 0.80 | ALDH1A1 (0.53) | ALDH1A1AHRTSHRCYP3A4HSD17B10 | |
| SCHEMBL11014169 | 0.75 | CYP3A4 (0.48) | ALDH1A1TSHRCYP3A4CD44TP53 | |
| SCHEMBL4304036 | 0.72 | ALDH1A1 (0.45) | ALDH1A1AHRTSHRCYP3A4HSD17B10 | |
| SCHEMBL180195 | 0.72 | ALDH1A1 (0.61) | RAPGEF4ALDH1A1AHRTSHRCYP3A4 | |
| SCHEMBL1828947 | 0.72 | RAPGEF4 (0.46) | RAPGEF4ALDH1A1AHRTSHRCYP3A4 | |
| SCHEMBL29351204 | 0.72 | ALDH1A1 (0.61) | RAPGEF4ALDH1A1AHRTSHRCYP3A4 | |
| SCHEMBL1505303 | 0.70 | RAPGEF4 (0.45) | RAPGEF4ALDH1A1AHRTSHRCYP3A4 | |
| SCHEMBL28475506 | 0.70 | ALDH1A1 (0.43) | ALDH1A1AHRTSHRCYP3A4HSD17B10 | |
| SCHEMBL28753398 | 0.70 | SHBG (0.34) | MAPT | |
| SCHEMBL23699497 | 0.69 | AKR1C4 (0.47) | ALDH1A1TSHRCYP3A4HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613878-B1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2016-07-27 | — | — | EP | disclosed |
| US-8716488-B2 | Olefin metathesis catalysts | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2014-05-06 | — | — | US | disclosed |
| US-20130023665-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2013-01-24 | — | — | US | disclosed |
| EP-0544732-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG, Peter K. (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003447-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG PETER K (US) | 1992-03-05 | — | — | WO | disclosed |
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4727178-A | Process for preparing phosphorodichloridothiolate | STAUFFER CHEMICAL CO. (US) | 1988-02-23 | — | — | US | disclosed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023665-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | OCIAD2, OCIAD1, OXER1 | RAPGEF4 773/4885ALDH1A1 1398/4885AHR 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.