Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500894 | 1.00 | LAP3 (0.42) | LAP3ANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL9498619 | 1.00 | LAP3 (0.42) | LAP3ANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL9500855 | 0.99 | LAP3 (0.41) | LAP3ANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL9500612 | 0.98 | LAP3 (0.42) | LAP3ANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL9500847 | 0.95 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL9498914 | 0.85 | LAP3 (0.54) | LAP3ANPEPRNPEPDNPEPLTA4H | |
| Hydrochloric Acid SCHEMBL9500443 | 0.83 | HTT (0.38) | LAP3ANPEPRNPEPDNPEPEPHX1 | |
| SCHEMBL9502271 | 0.79 | ECE1 (0.38) | ITGB1ITGA4ECE1 | |
| SCHEMBL9499477 | 0.78 | CYP3A4 (0.46) | CYP1A2SMN1; SMN2 | |
| SCHEMBL9500871 | 0.74 | EPHX1 (0.42) | EPHX1ITGB1ITGA4CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |